P144: Review of Deep Brain Stimulation Target Areas in Patients with Obsessive-Compulsive Disorder

p144: review of deep brain stimulation target areas in patients with obsessive-compulsive disorder

obsessive-compulsive disorder (ocd) is a psychiatric disorder manifested by thoughts and impulses that produce anxiety and result in patients performing repetitive rituals. treatment generally consists of cognitive behavioral intervention and serotonin reuptake inhibitors. up to 40% of patients will have functional impairment that significantly affects their quality of life. in the late 1990’s,...

Deep brain stimulation in obsessive-compulsive disorder.

The use of deep brain stimulation in psychiatric disorders has received great interest owing to the small risk of the operation, the reversible nature of the technique, and the possibility of optimizing treatment postoperatively. Currently, deep brain stimulation in psychiatry is investigated for obsessive-compulsive disorder, Gilles de la Tourette's syndrome, and major depression. This chapter...

Long-term deep-brain stimulation treatment for obsessive-compulsive disorder.

Cognitive effects of deep brain stimulation in patients with obsessive-compulsive disorder.

BACKGROUND Deep brain stimulation (DBS) is a promising treatment for treatment-refractory obsessive-compulsive disorder (OCD). However, the effects of DBS on cognitive functioning remain unclear. Therefore, we aimed to assess cognitive safety of DBS for treatment-refractory OCD and the association between clinical changes and cognitive functioning. METHODS Patients with treatment-refractory O...

The cost-effectiveness of deep brain stimulation for patients with treatment-resistant obsessive-compulsive disorder

BACKGROUND Obsessive-compulsive disorder (OCD) is a chronic neuropsychiatric disorder with a 2% to 3% lifetime prevalence; in addition, 10% of OCD patients are resistant to conventional therapy. Deep brain stimulation (DBS) has been an effective treatment for treatment resistant OCD patients (TROCD). We aimed to determine the cost-effectiveness of DBS for TROCD. METHODS We used a Markov model...

Deep brain stimulation for treatment-refractory obsessive compulsive disorder: a systematic review

BACKGROUND Obsessive-compulsive disorder is one of the most disabling of all psychiatric illnesses. Despite available pharmacological and psychotherapeutic treatments about 10% of patients remain severely affected and are considered treatment-refractory. For some of these patients deep brain stimulation offers an appropriate treatment method. The scope of this article is to review the published...